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Factors
in Sterile Compounding
1. O'Brien Pharmacy compounds solutions in concentrations and combinations
that are not commercially available.
A. Equivalent milligrams of commercial solutions are frequently
50% to 300% more expensive, and the volume required prohibits use.
2. Sterile solutions
from raw materials are considered the highest risk category by the
USP and ASHP.
A. As such we meet, but mostly exceed, USP, ASHP and Board of Pharmacy
regulations, and have the policies and procedures and documentation
to verify.
3. Individual
parameters include:
A. Compatibility
B. Solubility
C. Sterility
D. Pyrogenicity
E. Endotoxins
F. pH
G. Isotonicity
4. Our equipment
and training are state of the art and consistently updated.
5. Examples
of maximum concentrations include:
A. Fentanyl 1,750mcg/ml
B. Bupivacaine 30mg/ml
C. Clonidine 3,000mcg/ml
D. Baclofen 3,000mcg/ml
E. Morphine 100mg/ml (Potential drug concentrations/combinations
are too numerous to list)
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